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The principal cytochrome P450 isoenzyme involved appears for being CYP2E1, with CYP1A2 and CYP3A4 as added pathways. Around 85% of an oral dose seems from the urine within just 24 hours of administration, most since the glucuronide conjugate, with compact quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity information.To